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Severe sensitivity loss in an influenza A molecular assay due to antigenic drift variants during the 2014/15 influenza season.

Diagnostic microbiology and infectious disease - 1 May 2016

Overmeire Yarah, Vanlaere Elke, Hombrouck Anneleen, De Beenhouwer Hans, Simons Guus, Brink Antoinette, Van den Abeele Anne-Marie, Verfaillie Charlotte, Van Acker Jos

Abstract excerpt

The 2014-2015 influenza season in Belgium was dominated by the circulation of 2 influenza A(H3N2) subgroups: 3C.2a and 3C.3b. Analysis of 166 nasopharyngeal aspirates, collected in patients with respiratory illness at the start of the epidemic season, showed a decreased sensitivity for the detection of influenza A(H3N2)/3C.2a using a commercially available multiplex assay. Gene sequencing of the matrix protein...

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Identifiers

PMID: 26964723
DOI: 10.1016/j.diagmicrobio.2016.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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