Article
Desmopressin in moderate hemophilia A patients: a treatment worth considering.
Haematologica - 1 Mar 2018
Loomans Janneke I, Kruip Marieke J H A, Carcao Manuel, Jackson Shannon, van Velzen Alice S, Peters Marjolein, Santagostino Elena, Platokouki Helen, Beckers Erik, Voorberg Jan, van der Bom Johanna G, Fijnvandraat Karin
Abstract excerpt
Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed. Patients with a lower baseline factor VIII activity tend to show a reduced response, therefore, desmopressin is less frequently used in moderate hemophilia A patients (baseline factor VIII activity 1-5 international units/deciliter), even though factor VIII levels may...
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