Article
Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study.
Blood - 15 Mar 2004
Federici Augusto B, Mazurier Claudine, Berntorp Erik, Lee Christine A, Scharrer Inge, Goudemand Jenny, Lethagen Stephan, Nitu Ioana, Ludwig Gerard, Hilbert Lysiane, Mannucci Pier M
Abstract excerpt
This study prospectively evaluated the rate of biologic response to desmopressin (DDAVP) in 66 patients with type 1 or 2 von Willebrand disease (VWD), each of whom had, on the basis of available records, a clinically significant bleeding history and at least one of the following laboratory abnormalities: bleeding time (BT) longer than 15 minutes, ristocetin cofactor activity (VWF:RCo) less than 10 IU/dL, factor...
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