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Mitochondrial Dysfunction and Cognitive Impairment in Schizophrenia: The Role of Inflammation

13 Nov 2024

Abstract excerpt

BACKGROUND AND HYPOTHESIS: The complex immune-brain interactions and the regulatory role of mitochondria in the immune response suggest that mitochondrial damage reported in schizophrenia (SZ) may be related to abnormalities observed in immune and brain functions. STUDY DESIGN: Mitochondrial DNA copy number (mtDNA CN), a biomarker of mitochondrial function, was assessed in peripheral blood leukocytes (PBLs) of...

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PMID: 39535935
DOI: 10.1093/schbul/sbae196

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