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Pharmacogenetics of Vascular Risk Factors in Alzheimer’s Disease

3 Jan 2018

Abstract excerpt

Alzheimer’s disease (AD) is a polygenic/complex disorder in which genomic, epigenomic, cerebrovascular, metabolic, and environmental factors converge to define a progressive neurodegenerative phenotype. Pharmacogenetics is a major determinant of therapeutic outcome in AD. Different categories of genes are potentially involved in the pharmacogenetic network responsible for drug efficacy and safety, including...

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PMID: 29301387
DOI: 10.3390/jpm8010003

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