Article
Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population.
Behavioral and brain functions : BBF - 3 Jan 2018
Yang Yongfeng, Yu Hongyan, Li Wenqiang, Liu Bing, Zhang Hongxing, Ding Shuang, Lu Yanli, Jiang Tianzi, Lv Luxian
Abstract excerpt
BACKGROUND: Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Dopamine dysfunction is one of the pathogenesis of SZ. However, the relationship between CDNF2 and SZ has not been previously investigated. We speculated that CDNF2 may be a susceptibility...
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