Article
HIV-1 Subtypes and 5'LTR-Leader Sequence Variants Correlate with Seroconversion Status in Pumwani Sex Worker Cohort.
Viruses - 23 Dec 2017
Sampathkumar Raghavan, Scott-Herridge Joel, Liang Binhua, Kimani Joshua, Plummer Francis A, Luo Ma
Abstract excerpt
Within the Pumwani sex worker cohort, a subgroup remains seronegative, despite frequent exposure to HIV-1; some of them seroconverted several years later. This study attempts to identify viral variations in 5'LTR-leader sequences (5'LTR-LS) that might contribute to the late seroconversion. The 5'LTR-LS contains sites essential for replication and genome packaging, viz, primer binding site (PBS), major splice...
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