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Article

Optogenetic termination of atrial fibrillation in mice.

Cardiovascular research - 1 Apr 2018

Bruegmann Tobias, Beiert Thomas, Vogt Christoph C, Schrickel Jan W, Sasse Philipp

Abstract excerpt

Aims: The primary goal in the treatment of symptomatic atrial fibrillation/flutter (AF) is to restore sinus rhythm by cardioversion. Electrical shocks are highly effective, but have to be applied under analgo-sedation and can further harm the heart. In order to develop a novel pain-free and less harmful approach, we explored herein the optogenetic cardioversion by light-induced depolarization. Methods and...

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Source

Identifiers

PMID: 29293898
DOI: 10.1093/cvr/cvx250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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