Article
Systemic Profiling of KDM5 Subfamily Signature in Non-Small-Cell Lung Cancer
1 Oct 2021
Abstract excerpt
BACKGROUND: Despite improvements in diagnosis and treatment, lung cancer is one of the most lethal human diseases, with a dismal 5-year relative survival rate of only 5% for patients diagnosed with advanced metastatic disease. Accumulating evidence supports that epigenetic aberration of histone demethylase-KDM5 subfamily is linked to human pan-cancer. However, the detailed functions of KDM5 proteins in lung...
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