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Article

KDM6B promotes ESCC cell proliferation and metastasis by facilitating C/EBPβ transcription

17 May 2021

Abstract excerpt

BACKGROUND: As an H3K27me3 demethylase and counteracts polycomb-mediated transcription repression, KDM6B has been implicated in the development and malignant progression in various types of cancers. However, its potential roles in esophageal squamous cell carcinoma (ESCC) have not been explored. METHODS: The expression of KDM6B in human ESCC tissues and cell lines was examined using RT-qPCR, immunohistochemical...

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PMID: 34001062
DOI: 10.1186/s12885-021-08282-w

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