Article
Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer (Review)
30 Oct 2017
Abstract excerpt
Human papillomaviruses (HPVs) are double stranded circular DNA viruses that infect cutaneous and mucosal epithelial cells. Almost 99% of cervical cancer has a HPV infection. The early oncoproteins E6 and E7 are important in this cellular transformation process. Epigenetic mechanisms have long been known to result in decisive alterations in DNA, leading to alterations in DNA-protein interactions, alterations in...
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