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Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)

16 Apr 2014

Abstract excerpt

Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus (HPV) infection, which induces changes in the host genome and epigenome. Epigenetic alterations, such as aberrant miRNA expression and changes in DNA methylation status, favor the expression of...

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PMID: 24737381
DOI: 10.3892/or.2014.3142

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