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Article

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition.

Cell reports - 26 Dec 2017

Lemire Paul, Robertson Susan J, Maughan Heather, Tattoli Ivan, Streutker Catherine J, Platnich Jaye M, Muruve Daniel A, Philpott Dana J, Girardin Stephen E

Abstract excerpt

NLRP6 is a Nod-like receptor expressed in the intestinal epithelium. Previous studies reported a protective role for NLRP6 against intestinal injury and colitis-associated carcinogenesis via the regulation and establishment of a healthy microbiota. However, these results were not obtained using littermate animals, leaving the possibility that the pro-colitogenic microbiota phenotype associated with knockout (KO)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29281815
DOI: 10.1016/j.celrep.2017.12.026

Genes

NLRP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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