Article
KIR3DL1 alleles and their epistatic interactions with human leukocyte antigen class I influence resistance and susceptibility to HIV-1 acquisition in the Pumwani sex worker cohort.
AIDS (London, England) - 24 Apr 2018
Luo Ma, Czarnecki Chris, Nebroski Michelle, Kimani Joshua, Bernard Nicole, Plummer Francis A
Abstract excerpt
OBJECTIVE: To determine the associations of KIR3DL1/S1(3DL1/S1) and its epistatic interactions with human leukocyte antigen class I (HLA-I) alleles with resistance and susceptibility to HIV-1. DESIGN: Despite repeated exposure to HIV-1, a subset of women enrolled in the Pumwani sex worker cohort remain HIV uninfected. Previous studies have shown that specific HLA class I and II alleles were associated with this...
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