Article
Lack of association between rrl and erm(41) mutations and clarithromycin resistance in Mycobacterium abscessus complex.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2017
Carneiro Maiara Dos Santos, Nunes Luciana de Souza, David Simone Maria Martini de, Barth Afonso Luis
Abstract excerpt
BACKGROUND: Mycobacterium abscessus complex (MABC) includes species with high resistance rates among mycobacterial pathogens. In fact, MABC infections may not respond to clarithromycin treatment, which has historically been very effective against MABC infection. Molecular markers have been proposed to detect both acquired (rrl polymorphisms) and inducible (erm(41) polymorphisms) clarithromycin resistance in MABC...
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