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Article

A real-time PCR assay for rapid identification of inducible and acquired clarithromycin resistance in Mycobacterium abscessus.

BMC infectious diseases - 10 Dec 2020

Sharma Meenu Kaushal, La Yanni, Janella Debra, Soualhine Hafid

Abstract excerpt

BACKGROUND: Mycobacterium abscessus is a rapidly growing mycobacteria involved in severe infections of the lung, skin, or soft tissue. Macrolides such as clarithromycin are the recommended first line drugs for treatment of M. abscessus infections. However, M. abscessus has dual mechanisms of resistance to macrolides, making treatment by macrolides difficult. A functional erm(41) gene confers for inducible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33302900
DOI: 10.1186/s12879-020-05686-0
PMCID: PMC7730737

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