Article
Rapid Detection of Acquired and Inducible Clarithromycin Resistance in Mycobacterium abscessus Group by a Simple Real-Time PCR Assay.
Journal of clinical microbiology - 1 Jul 2015
Luo Robert F, Curry Cheyenne, Taylor Nathan, Budvytiene Indre, Banaei Niaz
Abstract excerpt
By targeting the erm(41) and rrl genes in the Mycobacterium abscessus group, a multiplex real-time PCR assay for clarithromycin resistance showed 95% (38/40) concordance with nucleic acid testing and 95% (37/39) concordance with phenotypic testing. This assay provides a simple and rapid alternative to extended incubation or erm(41) sequencing.
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