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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of <i> p16 <sup>INK4a</sup> </i>

2023-05-22

Abstract excerpt

Glaucoma is a leading cause of irreversible blindness, with advanced age being the single most significant risk factor. However, the mechanisms underlying the relationship between aging and glaucoma remain unclear. Genome-wide association studies (GWAS) have successfully identified genetic variants strongly associated with increased glaucoma risk. Understanding how these variants function in pathogenesis is crucia...

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Literature Corpus work
43c59f93-3dc8-5327-ad4a-9be4813d4e99
DOI
10.1101/2023.05.18.541339
Open publication

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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of <i> p16 <sup>INK4a</sup> </i>DOI 10.1101/2023.05.18.541339
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