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Article

A comprehensive analysis on preservation patterns of gene co-expression networks during Alzheimer’s disease progression

1 Dec 2017

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a chronic neuro-degenerative disruption of the brain which involves in large scale transcriptomic variation. The disease does not impact every regions of the brain at the same time, instead it progresses slowly involving somewhat sequential interaction with different regions. Analysis of the expression patterns of the genes in different regions of the brain influenced in AD...

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PMID: 29262769
DOI: 10.1186/s12859-017-1946-8

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