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Article

Concerted perturbation observed in a hub network in Alzheimer's disease.

PloS one - 1 Jan 2012

Liang Dapeng, Han Guangchun, Feng Xuemei, Sun Jiya, Duan Yong, Lei Hongxing

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disease involving the alteration of gene expression at the whole genome level. Genome-wide transcriptional profiling of AD has been conducted by many groups on several relevant brain regions. However, identifying the most critical dys-regulated genes has been challenging. In this work, we addressed this issue by deriving critical genes from perturbed...

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Identifiers

PMID: 22815752
DOI: 10.1371/journal.pone.0040498
PMCID: PMC3398025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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