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Detecting Diagnostic Biomarkers of Alzheimer's Disease by Integrating Gene Expression Data in Six Brain Regions

12 Mar 2019

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative and progressive disease, which often causes irreversible damages to the cerebrum. The pathogenesis of AD is far from being fully understood, while there are some popular hypotheses. So far, the diagnosis of AD relies only on clinical screening in the form of imaging techniques or cerebrospinal fluid analysis, which may lead to inaccurate evaluation and then cause...

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PMID: 30915100
DOI: 10.3389/fgene.2019.00157

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