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Article

Shannon entropy approach reveals relevant genes in Alzheimer's disease.

PloS one - 1 Jan 2019

Monaco Alfonso, Amoroso Nicola, Bellantuono Loredana, Lella Eufemia, Lombardi Angela, Monda Anna, Tateo Andrea, Bellotti Roberto, Tangaro Sabina

Abstract excerpt

Alzheimer's disease (AD) is the most common type of dementia and affects millions of people worldwide. Since complex diseases are often the result of combinations of gene interactions, microarray data and gene co-expression analysis can provide tools for addressing complexity. Our study aimed to find groups of interacting genes that are relevant in the development of AD. In this perspective, we implemented a...

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PMID: 31891941
DOI: 10.1371/journal.pone.0226190
PMCID: PMC6938408

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