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Protein kinase A governs growth and virulence in Candida tropicalis

19 Dec 2017

Abstract excerpt

Candida tropicalis is one of the most important human fungal pathogens causing superficial infections in locations such as the oral mucosa and genital tract, as well as systemic infections with high mortality. In its sister species Candida albicans, the cyclic AMP/protein kinase A (cAMP/PKA) pathway regulates fungal adhesion and dimorphism, both of which correlate closely with virulence. CaTpk1 and CaTpk2, the...

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PMID: 29254431
DOI: 10.1080/21505594.2017.1414132

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