Article
Protein kinase A encoded by TPK2 regulates dimorphism of Candida albicans.
Molecular microbiology - 1 Jan 2000
Sonneborn A, Bockmühl D P, Gerads M, Kurpanek K, Sanglard D, Ernst J F
Abstract excerpt
External signals induce the switch from a yeast to a hyphal growth form in the fungal pathogen Candida albicans. We demonstrate here that the catalytic subunit of a protein kinase A (PKA) isoform encoded by TPK2 is required for internal signalling leading to hyphal differentiation. TPK2 complemen...
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