Article
Cell-to-cell variation and specialization in sugar metabolism in clonal bacterial populations.
PLoS genetics - 1 Dec 2017
Nikolic Nela, Schreiber Frank, Dal Co Alma, Kiviet Daniel J, Bergmiller Tobias, Littmann Sten, Kuypers Marcel M M, Ackermann Martin
Abstract excerpt
While we have good understanding of bacterial metabolism at the population level, we know little about the metabolic behavior of individual cells: do single cells in clonal populations sometimes specialize on different metabolic pathways? Such metabolic specialization could be driven by stochastic gene expression and could provide individual cells with growth benefits of specialization. We measured the degree of...
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