Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial adenomatous polyposis in two brothers with hepatoblastoma: implications for diagnosis and screening.

Pediatric blood & cancer - 1 Nov 2006

Sanders Robert P, Furman Wayne L

Abstract excerpt

Two brothers with hepatoblastoma were noted to have a family history of early onset colon cancer. Genetic testing of the younger brother revealed a deletion in exon 15 of the adenomatous polyposis coli (APC) gene (2710-2711delAG), consistent with a diagnosis of familial adenomatous polyposis (FAP). We review the clinical and molecular aspects of the relationship between hepatoblastoma and FAP, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Antineoplastic Combined Chemotherapy Protocols

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biopsy, Needle

Share to Genes, APC

Share to Hepatoblastoma

Share to Remission Induction

Share to Siblings

Share to Tomography, X-Ray Computed

Source

Identifiers

PMID: 16106429
DOI: 10.1002/pbc.20556

Genes

FAP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial adenomatous polyposis in two brothers with hepatoblastoma: implications for diagnosis and screening.PMID 16106429Read ↗

Hepatoblastoma in patients with molecularly proven familial adenomatous polyposis: Clinical characteristics and rationale for surveillance screeningSemantic proximity Read ↗

Familial adenomatous polyposis.Semantic proximity Read ↗

Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate.Semantic proximity Read ↗

Colorectal adenomatous polyposis syndromes: Genetic determinism, clinical presentation and recommendations for care.Semantic proximity Read ↗

Familial Adenomatous PolyposisSemantic proximity Read ↗

Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood.Semantic proximity Read ↗

Genetics, genomics and clinical features of adenomatous polyposis.Semantic proximity Read ↗

Adenomatous Polyposis Coli Gene Polyposis-Related Syndromes.Semantic proximity Read ↗

Gastrointestinal Polyposis SyndromesSemantic proximity Read ↗

The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.Semantic proximity Read ↗

Could APC gene screening be useful in children with hepatoblastoma? Early onset of adenocarcinoma in a child with familial adenomatous polyposis and hepatoblastoma.Semantic proximity Read ↗

Paired Somatic-Germline Testing of 15 Polyposis and Colorectal Cancer-Predisposing Genes Highlights the Role of APC Mosaicism in de Novo Familial Adenomatous Polyposis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.