Article
Microencapsulated macrophages releases conditioned medium able to prevent epithelial to mesenchymal transition.
Drug delivery - 1 Nov 2018
Sola Anna, Saenz Del Burgo Laura, Ciriza Jesús, Hernandez Rosa Maria, Orive Gorka, Martin Cordero Jorge, Calle Priscila, Pedraz Jose Luis, Hotter Georgina
Abstract excerpt
Epithelial to mesenchymal transition (EMT) has emerged as a key process in the development of renal fibrosis. In fact, EMT-derived fibroblasts contribute to the progression of chronic renal disease. In addition, anti-inflammatory M2 macrophages have exhibited a great influence on renal fibrosis. However, because of the high impact that the inputs of different environmental cytokines have on their phenotype,...
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