Article
M1 and M2 macrophage recruitment during tendon regeneration induced by amniotic epithelial cell allotransplantation in ovine.
Research in veterinary science - 1 Apr 2016
Mauro Annunziata, Russo Valentina, Di Marcantonio Lisa, Berardinelli Paolo, Martelli Alessandra, Muttini Aurelio, Mattioli Mauro, Barboni Barbara
Abstract excerpt
Recently, we have demonstrated that ovine amniotic epithelial cells (oAECs) allotransplanted into experimentally induced tendon lesions are able to stimulate tissue regeneration also by reducing leukocyte infiltration. Amongst leukocytes, macrophages (Mφ) M1 and M2 phenotype cells are known to mediate inflammatory and repairing processes, respectively. In this research it was investigated if, during tendon...
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