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Article

Essential roles of stat5.1/stat5b in controlling fish somatic growth.

Journal of genetics and genomics = Yi chuan xue bao - 20 Dec 2017

Xiong Shuting, Mei Jie, Huang Peipei, Jing Jing, Li Zhi, Kang Jingliang, Gui Jian-Fang

Abstract excerpt

Signal transducer and activator of transcription 5b (STAT5b) has been identified as a key downstream mediator of growth hormone (GH) signaling in somatic growth of mammalian. However, the corresponding homologue gene of Stat5b is unknown in fish species. In this study, we generated loss-of-function mutants in stat5.1 and stat5.2, two stat5 homologues existing in zebrafish. In stat5.1-deficient zebrafish, a...

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Identifiers

PMID: 29246863
DOI: 10.1016/j.jgg.2017.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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