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Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy

13 Dec 2017

Abstract excerpt

Human pluripotent stem cells (PSCs) provide a promising resource to produce immune cells for adoptive cellular immunotherapy to better treat and potentially cure otherwise lethal cancers. Cytotoxic T cells and natural killer (NK) cells can now be routinely produced from human PSCs. These PSC-derived lymphocytes have phenotype and function similar to primary lymphocytes isolated from peripheral blood. PSC-derived...

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PMID: 29235195
DOI: 10.1002/stem.2754

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