Article
The Arabidopsis ALF4 protein is a regulator of SCF E3 ligases.
The EMBO journal - 17 Jan 2018
Bagchi Rammyani, Melnyk Charles W, Christ Gideon, Winkler Martin, Kirchsteiner Kerstin, Salehin Mohammad, Mergner Julia, Niemeyer Michael, Schwechheimer Claus, Calderón Villalobos Luz Irina A, Estelle Mark
Abstract excerpt
The cullin-RING E3 ligases (CRLs) regulate diverse cellular processes in all eukaryotes. CRL activity is controlled by several proteins or protein complexes, including NEDD8, CAND1, and the CSN Recently, a mammalian protein called Glomulin (GLMN) was shown to inhibit CRLs by binding to the RING BOX (RBX1) subunit and preventing binding to the ubiquitin-conjugating enzyme. Here, we show that Arabidopsis ABERRANT...
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