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Article

AXL and AXR1 have redundant functions in RUB conjugation and growth and development in Arabidopsis.

The Plant journal : for cell and molecular biology - 1 Oct 2007

Dharmasiri Nihal, Dharmasiri S, Weijers D, Karunarathna N, Jurgens G, Estelle M

Abstract excerpt

Cullin-RING ubiquitin-protein ligases such as the Skp1, cullin, F-box protein (SCF) have been implicated in many growth and developmental processes in plants. Normal SCF function requires that the CUL1 subunit be post-translationally modified by related to ubiquitin (RUB), a protein related to ubiquitin. This process is mediated by two enzymes: the RUB-activating and RUB-conjugating enzymes. In Arabidopsis, the...

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Source

Identifiers

PMID: 17655650
DOI: 10.1111/j.1365-313X.2007.03211.x

Genes

AXL
CUL1

Provenance

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Related research

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Research trail→

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AXL and AXR1 have redundant functions in RUB conjugation and growth and development in Arabidopsis.PMID 17655650Read ↗

AXR1-ECR1 and AXL1-ECR1 heterodimeric RUB-activating enzymes diverge in function in Arabidopsis thaliana.Semantic proximity Read ↗

AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response.Semantic proximity Read ↗

The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis.Semantic proximity Read ↗

Mutation of E1-CONJUGATING ENZYME-RELATED1 decreases RELATED TO UBIQUITIN conjugation and alters auxin response and development.Semantic proximity Read ↗

Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function.Semantic proximity Read ↗

Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function.Semantic proximity Read ↗

Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1.Semantic proximity Read ↗

Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis.Semantic proximity Read ↗

The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects.Semantic proximity Read ↗

Characterization of a novel temperature-sensitive allele of the CUL1/AXR6 subunit of SCF ubiquitin-ligases.Semantic proximity Read ↗

The Arabidopsis ALF4 protein is a regulator of SCF E3 ligases.Semantic proximity Read ↗

Isolation and characterization of cul1-7, a recessive allele of CULLIN1 that disrupts SCF function at the C terminus of CUL1 in Arabidopsis thaliana.Semantic proximity Read ↗

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