The FTO gene rs9939609 obesity-risk allele and loss of control over eating.

doi:10.3945/ajcn.2009.28439

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Article

The FTO gene rs9939609 obesity-risk allele and loss of control over eating.

The American journal of clinical nutrition - 1 Dec 2009

Tanofsky-Kraff Marian, Han Joan C, Anandalingam Kavitha, Shomaker Lauren B, Columbo Kelli M, Wolkoff Laura E, Kozlosky Merel, Elliott Camden, Ranzenhofer Lisa M, Roza Caroline A, Yanovski Susan Z, Yanovski Jack A

Abstract excerpt

BACKGROUND: Children with rs9939609 FTO variant alleles (homozygous = AA and heterozygous = AT) are predisposed to greater adiposity than are those with 2 wild-type alleles (TT). OBJECTIVE: Because FTO is highly expressed in hypothalamic regions that are important for appetite, FTO genotype may affect energy balance by influencing eating behavior. Loss of control (LOC) eating, a behavior commonly reported by...

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PMID: 19828706
DOI: 10.3945/ajcn.2009.28439
PMCID: PMC2777464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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