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Article

Prior systemic treatment increased the incidence of somatic mutations in metastatic breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2018

Fujii Takeo, Matsuda Naoko, Kono Miho, Harano Kenichi, Chen Huiqin, Luthra Rajyalakshmi, Roy-Chowdhuri Sinchita, Sahin Aysegul A, Wathoo Chetna, Joon Aron Y, Tripathy Debu, Meric-Bernstam Funda, Ueno Naoto T

Abstract excerpt

BACKGROUND: Understanding the biology of breast cancer is important for guiding treatment strategies and revealing resistance mechanisms. Our objectives were to investigate the relationship between previous systemic therapy exposure and mutational spectrum in metastatic breast cancer and to identify clinicopathological factors associated with identified frequent somatic mutations. METHODS: Archival tissues of...

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PMID: 29232568
DOI: 10.1016/j.ejca.2017.11.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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