Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

2 Dec 2017

Abstract excerpt

Human immunodeficiency virus (HIV) infection is associated with B-cell malignancies in patients though HIV-1 is not able to infect B-cells. The rate of B-cell lymphomas in HIV-infected individuals remains high even under the combined antiretroviral therapy (cART) that reconstitutes the immune function. Thus, the contribution of HIV-1 to B-cell oncogenesis remains enigmatic. HIV-1 induces oxidative stress and DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to Prion Diseases and Protein Misfolding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29220699
DOI: 10.1016/j.redox.2017.11.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS productionPMID 29220699Read ↗

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?Semantic proximity Read ↗

HIV-1 and HIV-1-Tat Induce Mitochondrial DNA Damage in Human NeuronsSemantic proximity Read ↗

Tat is a multifunctional viral protein that modulates cellular gene expression and functionsSemantic proximity Read ↗

Tits and bits of HIV Tat protein.Semantic proximity Read ↗

HIV-1 Transactivator of Transcription (Tat) Co-operates With AP-1 Factors to Enhance c-MYC TranscriptionSemantic proximity Read ↗

HIV-1 Tat induces DNMT over-expression through microRNA dysregulation in HIV-related non Hodgkin lymphomasSemantic proximity Read ↗

HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.Semantic proximity Read ↗

HIV Tat protein: Is Tat-C much trickier than Tat-B?Semantic proximity Read ↗

Chronic HIV‐1 Tat action induces HLA‐DR downregulation in B cells: A mechanism for lymphoma immune escape in people living with HIVSemantic proximity Read ↗

Impact of Tat Genetic Variation on HIV-1 DiseaseSemantic proximity Read ↗

Functions of Tat: the versatile protein of human immunodeficiency virus type 1Semantic proximity Read ↗

HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.