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HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?

7 Feb 2005

Abstract excerpt

The Tat protein of HIV-1 is a powerful activator of viral gene expression. Besides this essential function at the HIV-1 promoter, the protein also exerts a remarkable number of other biological activities, among which the induction of cellular apoptosis. Two papers now published in Retrovirology provide possible molecular mechanisms for the pro-apoptotic effect of Tat, which involve the cell's microtubular...

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PMID: 15698476
DOI: 10.1186/1742-4690-2-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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