Article
Cadm2 regulates body weight and energy homeostasis in mice.
Molecular metabolism - 1 Feb 2018
Yan Xin, Wang Zhen, Schmidt Vanessa, Gauert Anton, Willnow Thomas E, Heinig Matthias, Poy Matthew N
Abstract excerpt
OBJECTIVE: Obesity is strongly linked to genes regulating neuronal signaling and function, implicating the central nervous system in the maintenance of body weight and energy metabolism. Genome-wide association studies identified significant associations between body mass index (BMI) and multiple loci near Cell adhesion molecule2 (CADM2), which encodes a mediator of synaptic signaling enriched in the brain. Here...
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