Article
Evaluation of (fli:GFP) Casper Zebrafish Embryos as a Model for Human Conjunctival Melanoma.
Investigative ophthalmology & visual science - 1 Dec 2017
Pontes Kelly Cristine de Sousa, Groenewoud Arwin, Cao Jinfeng, Ataide Livia Maria Silva, Snaar-Jagalska Ewa, Jager Martine J
Abstract excerpt
Purpose: Conjunctival melanoma (CM) is a rare malignant disease that can lead to recurrences and metastases. There is a lack of effective treatments for the metastases, and we set out to develop a new animal model to test potential therapies. Zebrafish are being used as a model for many diseases, and our goal was to test whether this animal could be used to study CM. Methods: Three human CM cell lines (CRMM-1 and...
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