Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of dFOXO binding sites upstream of the Insulin Receptor P2 promoter across the Drosophila phylogeny.

PloS one - 1 Jan 2017

Orengo Dorcas J, Aguadé Montserrat, Juan Elvira

Abstract excerpt

The insulin/TOR signal transduction pathway plays a critical role in determining such important traits as body and organ size, metabolic homeostasis and life span. Although this pathway is highly conserved across the animal kingdom, the affected traits can exhibit important differences even between closely related species. Evolutionary studies of regulatory regions require the reliable identification of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Forkhead Transcription Factors

Share to Gene Expression Regulation

Share to Phosphorylation

Share to Receptor Protein-Tyrosine Kinases

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 29200426
DOI: 10.1371/journal.pone.0188357
PMCID: PMC5714339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of dFOXO binding sites upstream of the Insulin Receptor P2 promoter across the Drosophila phylogeny.PMID 29200426Read ↗

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling.Semantic proximity Read ↗

Understanding Forkhead Box Class O Function: Lessons from <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Long-range repression by ecdysone receptor on complex enhancers of the insulin receptor geneSemantic proximity Read ↗

Identification of FOXO targets that generate diverse features of the diapause phenotype in the mosquito Culex pipiens.Semantic proximity Read ↗

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans.Semantic proximity Read ↗

Genomics complement of FOXO1 gene prevents Type 2 DiabetesSemantic proximity Read ↗

Expression of Drosophila FOXO regulates growth and can phenocopy starvation.Semantic proximity Read ↗

Transcriptome Analysis of Insulin Signaling-Associated Transcription Factors in C. elegans Reveal Their Genome-Wide Target Genes Specificity and Complexity.Semantic proximity Read ↗

The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling.Semantic proximity Read ↗

FOXO3 and Related Transcription Factors in Development, Aging, and Exceptional LongevitySemantic proximity Read ↗

Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO.Semantic proximity Read ↗

Network-level molecular evolutionary analysis of the insulin/TOR signal transduction pathway across 12 Drosophila genomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.