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Article

Novel polymorphisms associated with hyperalphalipoproteinemia and apparent cardioprotection.

Journal of clinical lipidology - 1 Jan 2000

Oates Connor P, Koenig Darya, Rhyne Jeffrey, Bogush Nikolay, O'Connell Jeffrey, Mitchell Braxton D, Miller Michael

Abstract excerpt

BACKGROUND: Hyperalphalipoproteinemia (HALP) is inversely correlated with coronary heart disease (CHD) although genetic variants associated with high serum levels of high-density lipoprotein cholesterol (HDL-C) have not been shown to be cardioprotective. OBJECTIVE: The objective of the study was to uncover novel genetic variants associated with HALP and possibly with reduced risk of CHD. METHODS: Exome sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29198934
DOI: 10.1016/j.jacl.2017.10.021
PMCID: PMC5816714

Genes

ACACB
ANK2
LRP4
PLEKHH1
PLLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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