Article
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
European heart journal - 1 Feb 2012
Angelakopoulou Aspasia, Shah Tina, Sofat Reecha, Shah Sonia, Berry Diane J, Cooper Jackie, Palmen Jutta, Tzoulaki Ioanna, Wong Andrew, Jefferis Barbara J, Maniatis Nikolas, Drenos Fotios, Gigante Bruna, Hardy Rebecca, Laxton Ross C, Leander Karin, Motterle Anna, Simpson Iain A, Smeeth Liam, Thomson Andy, Verzilli Claudio, Kuh Diana, Ireland Helen, Deanfield John, Caulfield Mark, Wallace Chris, Samani Nilesh, Munroe Patricia B, Lathrop Mark, Fowkes F Gerry R, Marmot Michael, Whincup Peter H, Whittaker John C, de Faire Ulf, Kivimaki Mika, Kumari Meena, Hypponen Elina, Power Chris, Humphries Steve E, Talmud Philippa J, Price Jackie, Morris Richard W, Ye Shu, Casas Juan P, Hingorani Aroon D
Abstract excerpt
AIMS: To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association study-derived lipid-associated SNPs with other risk factors and CHD events. METHODS AND RESULTS: Using two case-control studies, three cross-sectional, and seven...
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