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Article

An expression screen for aged-dependent microRNAs identifies miR-30a as a key regulator of aging features in human epidermis.

Aging - 19 Nov 2017

Muther Charlotte, Jobeili Lara, Garion Maëlle, Heraud Sandrine, Thepot Amélie, Damour Odile, Lamartine Jérôme

Abstract excerpt

The mechanisms affecting epidermal homeostasis during aging remain poorly understood. To identify age-related microRNAs, a class of non-coding RNAs known to play a key role in the regulation of epidermal homeostasis, an exhaustive miRNA expression screen was performed in human keratinocytes from young or elderly subjects. Many microRNAs modulated by aging were identified, including miR-30a, in which both strands...

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Source

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Identifiers

PMID: 29165315
DOI: 10.18632/aging.101326
PMCID: PMC5723692

Genes

AVEN
IDH1
LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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