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Article

Narcolepsy susceptibility gene CCR3 modulates sleep-wake patterns in mice.

PloS one - 1 Jan 2017

Toyoda Hiromi, Honda Yoshiko, Tanaka Susumu, Miyagawa Taku, Honda Makoto, Honda Kazuki, Tokunaga Katsushi, Kodama Tohru

Abstract excerpt

Narcolepsy is caused by the loss of hypocretin (Hcrt) neurons and is associated with multiple genetic and environmental factors. Although abnormalities in immunity are suggested to be involved in the etiology of narcolepsy, no decisive mechanism has been established. We previously reported chemokine (C-C motif) receptor 3 (CCR3) as a novel susceptibility gene for narcolepsy. To understand the role of CCR3 in the...

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Source

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Identifiers

PMID: 29186205
DOI: 10.1371/journal.pone.0187888
PMCID: PMC5706730

Genes

CCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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