Article
Mutation analysis of EGFR and its correlation with the HPV in Indian cervical cancer patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016
Qureshi Rehana, Arora Himanshu, Biswas Shilpi, Perwez Ahmad, Naseem Afreen, Wajid Saima, Gandhi Gauri, Rizvi Moshahid Alam
Abstract excerpt
Cervical cancer is a major cause of morbidity and mortality particularly in developing countries. Somatic mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene is associated with increased sensitivity to tyrosine kinase inhibitors (TKIs). In this study, the presence of EGFR mutations in cervical cancer and its correlation with HPV were identified. EGFR mutations were found in...
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