Article
The role of the renin-angiotensin-aldosterone system in preeclampsia: genetic polymorphisms and microRNA.
Journal of molecular endocrinology - 1 Apr 2013
Yang Jie, Shang Jianyu, Zhang Suli, Li Hao, Liu Huirong
Abstract excerpt
The compensatory alterations in the rennin-angiotensin-aldosterone system (RAAS) contribute to the salt-water balance and sufficient placental perfusion for the subsequent well-being of the mother and fetus during normal pregnancy and is characterized by an increase in almost all the components of RAAS. Preeclampsia, however, breaks homeostasis and leads to a disturbance of this delicate equilibrium in RAAS both...
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