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Article

Interaction of HLA-DRB1* alleles and CTLA4 (+49 AG) gene polymorphism in Autoimmune Thyroid Disease.

Gene - 5 Feb 2018

Ramgopal Sivanadham, Rathika Chinniah, Padma Malini Ravi, Murali Vijayan, Arun Kannan, Kamaludeen Mohamed Nainar, Balakrishnan Karuppiah

Abstract excerpt

Autoimmune Thyroid Diseases (AITDs), including Hashimoto's thyroiditis (HT) and Graves' disease (GD), arise by the complex interaction of genes and environmental factors. The aim of present study was to study the susceptible associations of HLA-DRB1* alleles and CTLA4 +49 AG polymorphism in AITD in south India. AITD patients (n=235; HT=180; GD=55) and age/sex matched healthy controls (n, 235) were enrolled to...

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Source

Identifiers

PMID: 29174716
DOI: 10.1016/j.gene.2017.11.057

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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