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Article

Current update on molecular cytogenetics, diagnosis and management of gastrointestinal stromal tumors.

World journal of gastroenterology - 7 Nov 2021

Wang Mindy X, Devine Catherine, Segaran Nicole, Ganeshan Dhakshinamoorthy

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract and are thought to arise from precursors of the interstitial cells of Cajal. GISTs can arise anywhere in the GI tract, but most commonly originate from the stomach and small intestine. The majority of GISTs occur as a result of activating mutations in two receptor protein tyrosine kinases: KIT and/or...

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Identifiers

PMID: 34887632
DOI: 10.3748/wjg.v27.i41.7125
PMCID: PMC8613640

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