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Mitochondrial Dysfunction and Metabolic Reprogramming in Obesity and Asthma

3 Mar 2024

Abstract excerpt

Mitochondrial dysfunction and metabolic reprogramming have been extensively studied in many disorders ranging from cardiovascular to neurodegenerative disease. Obesity has previously been associated with mitochondrial fragmentation, dysregulated glycolysis, and oxidative phosphorylation, as well as increased reactive oxygen species production. Current treatments focus on reducing cellular stress to restore...

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PMID: 38474191
DOI: 10.3390/ijms25052944

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