Article
Recognition of rare hemoglobin variants by hemoglobin A1c measurement procedures.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2018
Strickland Sydney W, Campbell Sean T, Little Randie R, Bruns David E, Bazydlo Lindsay A L
Abstract excerpt
BACKGROUND: Unrecognized hemoglobinopathies can lead to measured hemoglobin A1c (Hb A1c) concentrations that are erroneous or misleading. We determined the effects of rare hemoglobin variants on capillary electrophoresis (CE) and HPLC methods for measurement of Hb A1c. METHODS: We prospectively investigated samples in which Hb A1c was measured by CE during a 14-month period. For samples in which the...
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