Article
Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.
Clinical chemistry - 1 Feb 2001
Bry L, Chen P C, Sacks D B
Abstract excerpt
BACKGROUND: Glycohemoglobin (gHb), measured as hemoglobin (Hb) A(1c) or as total gHb, provides a common means for assessing long-term glycemic control in individuals with diabetes mellitus. Genetic variants and chemically modified derivatives of Hb can profoundly affect the accuracy of these measurements, although effects vary considerably among commercially available methods. The prevalence of genetic variants...
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